{
  "access_links": 3475,
  "access_links_definition": "Number of access entries in registry-access.tsv for this registration, including source pages, metadata, retained queries and derived tables; not distinct experiments or a count of live-verified downloads.",
  "access_status_counts": {
    "link_available_not_live_verified": 2265,
    "public_linked": 2,
    "public_verified": 1208
  },
  "core_registry_join_scope": "Existing explicit target IDs plus independently reviewed, project-qualified SNCA branch links; source labels alone never establish reference identity.",
  "core_relationship_resolution": {
    "disposition": {
      "canonical_registry_modified": false,
      "connection_counts": {
        "connected_source_qualified": 2,
        "not_directly_connected": 16
      },
      "disposition_counts": {
        "connected": 2,
        "not_applicable": 12,
        "partially_resolved": 1,
        "proposal_prepared": 2,
        "resolved_material": 1
      },
      "format": "panapta-core-registry-disposition/v1",
      "historical_import_provenance_pending": 1,
      "human_scientific_approval_created": false,
      "independent_target_count_claimed": false,
      "material_identity_fully_adjudicated_claimed": false,
      "not_applicable_material_counts": {
        "cell_line_context": 6,
        "cell_line_group": 1,
        "extracellular_vesicle": 1,
        "islet_tissue": 2,
        "mixed_species_islet_context": 1,
        "treated_cell_line": 1
      },
      "not_applicable_means": {
        "en": "No direct single-protein registry match is required for these source-qualified materials. Material identities, controls and source aliases can still require curation; their data remain in the core catalogue.",
        "zh": "这些来源限定材料无需直接匹配单一蛋白登记；具体材料身份、对照和来源别名仍可继续整理，其数据保留在核心目录中。"
      },
      "pending_means": {
        "en": "Three follow-ups remain: the original HeLa import log and review of two prepared registration proposals. The source-qualified mouse ST2 material relationship is resolved.",
        "zh": "三项后续事项为HeLa原始导入日志及两条已备齐的登记提案审核；鼠ST2来源限定材料关系已核清。"
      },
      "pending_reason_counts": {
        "simulation_reconstruction_complete_original_import_unresolved": 1,
        "source_qualified_registration_proposal_prepared": 2
      },
      "registration_proposals_prepared": 2,
      "registry_resolution_pending_groups": 3,
      "reviewed_source_groups": 18,
      "scientific_counts_changed": false,
      "scope": "Applicability to the existing single-protein reference registry; not scientific validity, source availability or exact material-identity completeness.",
      "source_data_removed": false,
      "source_evidence_updates": true,
      "source_evidence_url": "/web/source-evidence",
      "source_qualified_materials_resolved": 1,
      "target_ids_by_disposition": {
        "connected": [
          2614,
          2615
        ],
        "not_applicable": [
          79,
          80,
          81,
          82,
          83,
          84,
          3025,
          3026,
          3027,
          3028,
          3029,
          3030
        ],
        "partially_resolved": [
          2632
        ],
        "proposal_prepared": [
          2631,
          2633
        ],
        "resolved_material": [
          71
        ]
      }
    },
    "evidence_updates": {
      "hela": "simulation_reconstruction_complete_original_import_unresolved",
      "registration_proposals": 2,
      "st2": "resolved_source_qualified_mouse_material",
      "url": "/web/source-evidence"
    },
    "original_reason_categories": {
      "existing_cell_context_mixed_origin": 1,
      "existing_registry_connection_gap": 2,
      "nonprotein_material_not_in_registry": 12,
      "protein_reference_not_in_registry": 2,
      "species_reference_conflict": 1
    },
    "original_unmatched_groups_reviewed": 18,
    "reference_identity_approval_implied": false,
    "remaining_not_directly_connected": 16,
    "source_qualified_branch_links_added": 2
  },
  "distinct_linked_legacy_target_groups": 1020,
  "distinct_names": 676,
  "format": "panapta-registry-evidence-matrix/v1",
  "linked_aptamer_selection_candidate_records": 52344,
  "linked_aptamer_selection_target_groups": 9,
  "material_kind_counts": {
    "cell_context": 1,
    "mixed_constructs": 1,
    "protein_complex": 9,
    "protein_fragment": 6,
    "reference_only": 650,
    "source_named_material": 2,
    "unresolved": 6,
    "unresolved_complex": 2
  },
  "missing_reasons": [
    "not_verified",
    "source_not_identified",
    "not_applicable",
    "not_integrated",
    "not_reported",
    "unresolved_identity",
    "not_target_specific",
    "not_publicly_released"
  ],
  "no_positive_target_specific_support_entries": 12,
  "processed_aptamer_archive_raw_files": 408,
  "processed_aptamer_archive_runs": 390,
  "public_verification": {
    "base_url": "https://tmbj2.tail920732.ts.net",
    "checked_at": "2026-10-23T05:31:59.362323+00:00",
    "full_download_contents_rehashed": false,
    "matched_registry_source_associations": 1022,
    "native_download_head_size_checks": 125,
    "release_index_sha256": "3bfbfbd83ceed73f8a7125f475d515741dcc04040a0f9e75430a6af08055be7e",
    "retained_count_metadata_comparisons": 1022,
    "round_ids_and_read_totals_revalidated_by_public_api": false,
    "round_label_multisets_compared": 1018,
    "round_metadata_gets": 1018,
    "scope": "Public bulk target metadata identity tuples; each matched target round-metadata GET; all native-count download HEAD/size checks. No full file contents or sequence queries fetched.",
    "sequence_query_contents_checked": false
  },
  "registration_is_independent_experimental_target": false,
  "registrations_with_access_entries": 480,
  "registrations_with_retained_candidate_mapping": 434,
  "registrations_with_source_file_exports": 8,
  "registrations_without_access_entries": 197,
  "registry_entries": 677,
  "relation_counts": {
    "archive_lead_only": 2,
    "cell_context": 1,
    "complex_component": 8,
    "complex_identity_unresolved": 2,
    "prior_evidence_retained": 634,
    "reference_alias": 7,
    "reference_fragment": 4,
    "source_mismatch": 6,
    "source_named_target": 11,
    "source_unresolved": 2
  },
  "relationship_records": 1570,
  "scope_note": "All 677 registry entries are represented. Scientific support and website availability are separate. Project and file counts are contextual and cannot be added across registry rows.",
  "sequence_payloads_included": false,
  "snca_access_correction": {
    "full_archive_publication_claimed": false,
    "historical_metadata_conflicts_preserved": true,
    "proof_checked_at": "2026-10-23T08:20:48.343595+00:00",
    "public_derived_case_connected": true
  },
  "source_classification_correction": {
    "canonical_database_modified": false,
    "download_url": "/web/registry-evidence/download/source-classifications.json",
    "exact_construct_identity_verified": false,
    "per_sequence_chemical_identity_verified": false,
    "raw_library_type": "DNA",
    "raw_target_category": "cell",
    "source_library_type": "RNA",
    "source_material_type": "protein_fibril",
    "source_project": "PRJEB70964",
    "source_target_category": "protein",
    "target_ids": [
      2614,
      2615
    ]
  },
  "supported_or_qualified_entries": 665,
  "total_counts_additive_across_layers": false,
  "unique_public_source_count_files": 125,
  "unlinked_aptamer_selection_target_groups": 16,
  "version": "registry-evidence-matrix-20261024-r1",
  "whole_project_counts_assigned_to_registry_targets": false
}
