Pan-target SELEX aptamer atlas

PanApta re-processes raw SELEX reads into round-level count, frequency and enrichment tables across diverse protein, DNA and RNA targets — and overlays curated affinity records and structural features in one queryable resource.

Targets
57
protein-SELEX libraries
Sequences
140,000
aptamers (top by enrichment)
SELEX rounds
85
across all libraries
Round counts
850,000
long-format observations
Affinity rows
2,681
curated Kd / Ki / IC50

Targets in this release

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Target UniProt Source Rounds Sequences
BCMA
B-cell maturation antigen / TNFRSF17
Q02223 local 6 10,000
BRK
Breast tumor kinase / PTK6
Q13882 local 6 10,000
CRP
C-reactive protein
P02741 local 6 10,000
CTGF
Connective tissue growth factor
P29279 local 6 10,000
CTGF_new
CTGF (v2 library)
P29279 local 5 10,000
DKK1
Dickkopf-related protein 1
O94907 local 11 10,000
FGF23
Fibroblast growth factor 23
Q9GZV9 local 4 10,000
MSTN
Myostatin
O14793 local 3 10,000
MSTN_Cell
Myostatin (cell-displayed library)
O14793 local 10 10,000
MSTN_Ecoli
Myostatin (E. coli-purified protein library)
O14793 local 7 10,000
PCT
Procalcitonin
P01258 local 5 10,000
PTK7
Protein tyrosine kinase 7
Q13308 local 5 10,000

What sets PanApta apart

  • Round-level enrichment trajectories. Every sequence carries its full per-round count + frequency vector — not just a final-round abundance.
  • Re-processed from raw reads. Unified bioinformatics pipeline applied across 57 targets and 21+ public BioProjects.
  • Curated affinity overlay. 2,681 Kd/Ki/IC50 records merged from UTexas, AptamerBase, Ribocentre and PDB.
  • ML-ready protein context. ESM-2 embeddings and Boltz-2 surface descriptors linked per target.