Affinity records
Curated Kd, Ki, IC50, EC50 and other binding-related measurements from public sources. Measurement types remain explicit and should not be interpreted as interchangeable endpoints.
Total
2,681
With positive, finite nM value
2,565
AptamerBase
1,171
PDB
56
Ribocentre
360
UTexas
1,094
| Target | Aptamer | NA | Type | Relation | Reported value | Normalized (nM) | Source | Method | Year | PubMed |
|---|---|---|---|---|---|---|---|---|---|---|
| G-protein-coupled cholecystokinin B receptor (CCKBR) | — | DNA | Kd | = | 0.0155 | 0.0155 | UTexas | — | — | — |
| Interleukin-17A (IL‐17A) | — | RNA | Kd | = | 0.0485 | 0.0485 | UTexas | — | — | — |
| human interleukin 17A | 20967861-IL17A-1 | DNA | Kd | = | 4.85e-11 | 0.0485 | AptamerBase | — | — | 20967861 ↗ |
| Proinflammatory cytokine interleukin-17A (IL-17A) | Proinflammatory cytokine interleukin-17A (IL-17A)_Apt21‐2 | RNA | Kd | = | Kd: 48.5 pM | 0.0485 | Ribocentre | — | 2011 | 20967861 ↗ |
| Proinflammatory cytokine interleukin-17A (IL-17A) | Proinflammatory cytokine interleukin-17A (IL-17A)_Apt21-2 aptamer(truncation) | RNA | Kd | = | Kd: 48.5 pM | 0.0485 | Ribocentre | — | 2011 | 20967861 ↗ |
| mouse interleukin 17A | 20967861-IL17A-1 | DNA | Kd | = | 7.013e-10 | 0.7013 | AptamerBase | — | — | 20967861 ↗ |
| Protein Tyrosine Kinase-7 (PTK7) | — | DNA | Kd | = | 0.8 | 0.8 | UTexas | — | — | — |
| Chemokine CCL17 | — | RNA | Kd | = | 0.9 | 0.9 | UTexas | — | — | — |
| Chemokine CCL17 | Chemokine CCL17_MF11.46 | RNA | Kd | = | Kd: 0.9±0.1 nM | 0.9 | Ribocentre | — | 2018 | 29103909 ↗ |
| interleukin 17 RA | 21310253-IL17RA-2 | DNA | Kd | = | 1.2e-09 | 1.2 | AptamerBase | — | — | 21310253 ↗ |
| G-protein-coupled receptor kinase 2 (GRK2) | G-protein-coupled receptor kinase 2 (GRK2)_C13.28 aptamer | RNA | Kd | = | Kd: 1.2±0.6 nM | 1.2 | Ribocentre | — | 2012 | 22727813 ↗ |
| Interleukin-8 (IL-8) | — | RNA | Kd | = | 1.22 | 1.22 | UTexas | — | — | — |
| C-C motif chemokine 2 (L-CCL2) | C-C motif chemokine 2 (L-CCL2)_NOX-E36 L aptamer | RNA | Kd | = | Kd: 1.40±0.16 nM | 1.4 | Ribocentre | — | 2007 | 17625118 ↗ |
| IFN-gamma-inducible (IFN-γ-Inducible) mCXCL10 Chemokine (also known as IP-10 in humans and CRG-2 in mice) | — | RNA | Kd | = | 1.53 | 1.53 | UTexas | — | — | — |
| Interleukin-8 (IL-8) | — | RNA | Kd | = | 1.72 | 1.72 | UTexas | — | — | — |
| IFN-gamma-inducible (IFN-γ-Inducible) mCXCL10 Chemokine (also known as IP-10 in humans and CRG-2 in mice) | — | RNA | Kd | = | 1.76 | 1.76 | UTexas | — | — | — |
| Fractalkine (FKN) | — | DNA | Kd | = | 3.4 | 3.4 | UTexas | — | — | — |
| ERBB2 Receptor Protein-Tyrosine Kinase | 21644840-ErbB2-1 | RNA | Kd | = | 3.49e-09 | 3.49 | AptamerBase | — | — | 21644840 ↗ |
| IFN-gamma-inducible (IFN-γ-Inducible) mCXCL10 Chemokine (also known as IP-10 in humans and CRG-2 in mice) | — | RNA | Kd | = | 3.5 | 3.5 | UTexas | — | — | — |
| interleukin 17 RA | 21310253-IL17RA-4 | DNA | Kd | = | 3.8e-09 | 3.8 | AptamerBase | — | — | 21310253 ↗ |
| interleukin 17 RA | 21310253-IL17RA-5 | DNA | Kd | = | 4e-09 | 4 | AptamerBase | — | — | 21310253 ↗ |
| interleukin 17 RA | 21310253-IL17RA-3 | DNA | Kd | = | 4.3e-09 | 4.3 | AptamerBase | — | — | 21310253 ↗ |
| interleukin 17 RA | 21310253-IL17RA-1 | DNA | Kd | = | 5.9e-09 | 5.9 | AptamerBase | — | — | 21310253 ↗ |
| Protein kinase C beta II (protein kinase C βII) | — | RNA | Kd | = | 7 | 7 | UTexas | — | — | — |
| Protein kinase C beta II (protein kinase C βII) | — | RNA | Kd | = | 7 | 7 | UTexas | — | — | — |
| Protein kinase C beta II | Protein kinase C beta II_PKC 6 | RNA | Kd | = | Kd: 7 nM | 7 | Ribocentre | — | 1994 | 7528207 ↗ |
| Protein kinase C beta II | Protein kinase C beta II_PKC 10 | RNA | Kd | = | Kd: 7 nM | 7 | Ribocentre | — | 1994 | 7528207 ↗ |
| Chemokine CCL17 | — | RNA | Kd | = | 7.5 | 7.5 | UTexas | — | — | — |
| Chemokine CCL17 | Chemokine CCL17_MF35.47 | RNA | Kd | = | Kd: 7.5±1.5 nM | 7.5 | Ribocentre | — | 2018 | 29103909 ↗ |
| Interleukin 2 receptor alpha (IL2Rα CD25) | — | DNA | Kd | = | 13.4 | 13.4 | UTexas | — | — | — |
| Interleukin-6 receptor (IL-6R), Human | — | RNA | Kd | = | 23.1 | 23.1 | UTexas | — | — | — |
| Soluble pleiotropic cytokine interleukin-6 receptor (sIL-6R) and interleukin-6 receptor domain 3 (IL-6R D3) | — | RNA | Kd | = | 34.8 | 34.8 | UTexas | — | — | — |
| Interleukin-6 receptor domain 3 (IL-6R D3) | Interleukin-6 receptor domain 3 (IL-6R D3)_F4 | RNA | Kd | = | Kd: 34.8±5.8 nM | 34.8 | Ribocentre | — | 2015 | 26383776 ↗ |
| G-protein-coupled receptor kinase 2 (GRK2) | G-protein-coupled receptor kinase 2 (GRK2)_C13.18 aptamer | RNA | Kd | = | Kd: 35±5 nM | 35 | Ribocentre | — | 2012 | 22727813 ↗ |
| Soluble Interleukin 2 Receptor α (CD25) | — | RNA | Kd | = | 35.7 | 35.7 | UTexas | — | — | — |
| Interleukin 17 A/F | 21524680-IL17A/F-2 | RNA | Kd | = | 3.58e-08 | 35.8 | AptamerBase | — | — | 21524680 ↗ |
| Hyper-Interleukin-6 (IL-6) (a fusion protein of sIL-6R and IL-6) | — | RNA | Kd | = | 40.9 | 40.9 | UTexas | — | — | — |
| Cytokine (CK+, CK-) stimulated cells that cause Chronic Kidney Disease (CKD) | — | DNA | Kd | = | 46 | 46 | UTexas | — | — | — |
| Soluble Interleukin 2 Receptor α (CD25) | — | RNA | Kd | = | 46.1 | 46.1 | UTexas | — | — | — |
| G-protein-coupled receptor kinase 2 (GRK2) | G-protein-coupled receptor kinase 2 (GRK2)_C13.20 aptamer | RNA | Kd | = | Kd: 48±7 nM | 48 | Ribocentre | — | 2012 | 22727813 ↗ |
| Soluble pleiotropic cytokine interleukin-6 receptor (sIL-6R) and interleukin-6 receptor domain 3 (IL-6R D3) | — | RNA | Kd | = | 54.7 | 54.7 | UTexas | — | — | — |
| Vaccinia-related kinase (VRK1), Human | — | DNA | Kd | = | 60.06 | 60.06 | UTexas | — | — | — |
| Soluble Interleukin 2 Receptor α (CD25) | — | RNA | Kd | = | 68.2 | 68.2 | UTexas | — | — | — |
| Cytokine (CK+, CK-) stimulated cells that cause Chronic Kidney Disease (CKD) | — | DNA | Kd | = | 69 | 69 | UTexas | — | — | — |
| Interleukin 17 A/F | 21524680-IL17A/F-1 | RNA | Kd | = | 7.22e-08 | 72.2 | AptamerBase | — | — | 21524680 ↗ |
| dsRNA activated protein kinase | 9572845-PKR protein-6 | RNA | Kd | = | 7.4e-08 | 74 | AptamerBase | — | — | 9572845 ↗ |
| G-protein-coupled receptor kinase 2 (GRK2) | — | RNA | Kd | = | 78.2 | 78.2 | UTexas | — | — | — |
| Recombinant Human G-protein-coupled receptor kinase 2 | 18230760-GRK2-1 | DNA | Kd | = | 7.82e-08 | 78.2 | AptamerBase | — | — | 18230760 ↗ |
| G-protein-coupled receptor kinase 2 (GRK2) | G-protein-coupled receptor kinase 2 (GRK2)_C13 | RNA | Kd | = | Kd: 78.2 nM±2.6 nM | 78.2 | Ribocentre | — | 2008 | 18230760 ↗ |
| Cytokine (CK+, CK-) stimulated cells that cause Chronic Kidney Disease (CKD) | — | DNA | Kd | = | 82 | 82 | UTexas | — | — | — |
| Interleukin-8 (IL-8) | — | RNA | Kd | = | 92.2 | 92.2 | UTexas | — | — | — |
| Soluble Interleukin 2 Receptor α (CD25) | — | RNA | Kd | = | 96.9 | 96.9 | UTexas | — | — | — |
| Soluble pleiotropic cytokine interleukin-6 receptor (sIL-6R) and interleukin-6 receptor domain 3 (IL-6R D3) | — | RNA | Kd | = | 97.7 | 97.7 | UTexas | — | — | — |
| Interleukin-6 receptor domain 3 (IL-6R D3) | Interleukin-6 receptor domain 3 (IL-6R D3)_F2 | RNA | Kd | = | Kd: 97.7±18.3 nM | 97.7 | Ribocentre | — | 2015 | 26383776 ↗ |
| G-protein-coupled receptor kinase 2 (GRK2) | — | RNA | Kd | = | 101.2 | 101.2 | UTexas | — | — | — |
| Recombinant Human G-protein-coupled receptor kinase 2 | 18230760-GRK2-Ma-1 | RNA | Kd | = | 1.012e-07 | 101.2 | AptamerBase | — | — | 18230760 ↗ |
| G-protein-coupled receptor kinase 2 (GRK2) | G-protein-coupled receptor kinase 2 (GRK2)_C13.51 | RNA | Kd | = | Kd: 101.2 nM±7.2 nM | 101.2 | Ribocentre | — | 2008 | 18230760 ↗ |
| mutated form of the membrane receptor tyrosine kinase EC-RETC364Y-PA | 17155908-EC-RETC364Y-PA-1 | DNA | Kd | = | 1.04e-07 | 104 | AptamerBase | — | — | 17155908 ↗ |
| C-C chemokine receptor type 5 (CCR5 | — | RNA | Kd | = | 110 | 110 | UTexas | — | — | — |
| dsRNA activated protein kinase | 9572845-PKR protein-8 | RNA | Kd | = | 1.1e-07 | 110 | AptamerBase | — | — | 9572845 ↗ |
| Protein kinase C-delta (PKCδ) | — | DNA | Kd | = | 122 | 122 | UTexas | — | — | — |
| Soluble Interleukin 2 Receptor α (CD25) | — | RNA | Kd | = | 122 | 122 | UTexas | — | — | — |
| Protein kinase C delta | 17028752-Protein kinase C-delta-1 | DNA | Kd | = | 1.22e-07 | 122 | AptamerBase | — | — | 17028752 ↗ |
| Vaccinia-related kinase (VRK1), Human | — | DNA | Kd | = | 128.8 | 128.8 | UTexas | — | — | — |
| Interleukin 2 receptor alpha (IL2Rα CD25) | — | DNA | Kd | = | 138.6 | 138.6 | UTexas | — | — | — |
| Human p21-activated kinase | 20564698-Human p21-activated kinase-4 | DNA | Kd | = | 1.6e-07 | 160 | AptamerBase | — | — | 20564698 ↗ |
| Soluble pleiotropic cytokine interleukin-6 receptor (sIL-6R) and interleukin-6 receptor domain 3 (IL-6R D3) | — | RNA | Kd | = | 179 | 179 | UTexas | — | — | — |
| Interleukin-6 receptor domain 3 (IL-6R D3) | Interleukin-6 receptor domain 3 (IL-6R D3)_F3 | RNA | Kd | = | Kd: 179±117 nM | 179 | Ribocentre | — | 2015 | 26383776 ↗ |
| Human p21-activated kinase | 20564698-Human p21-activated kinase-1 | DNA | Kd | = | 2.1e-07 | 210 | AptamerBase | — | — | 20564698 ↗ |
| Interleukin 17 A/A | 21524680-IL17A/F-2 | RNA | Kd | = | 4.93e-07 | 493 | AptamerBase | — | — | 21524680 ↗ |
| polyphosphate kinase 2 | 21381755-Polyphosphate Kinase 2-1 | DNA | Kd | = | 8.7e-07 | 870 | AptamerBase | — | — | 21381755 ↗ |
| Interleukin 17 A/A | 21524680-IL17A/F-1 | RNA | Kd | = | 1.92e-06 | 1920 | AptamerBase | — | — | 21524680 ↗ |
| dsRNA activated protein kinase | 9572845-PKR protein-1 | RNA | Kd | = | 2.3e-06 | 2300 | AptamerBase | — | — | 9572845 ↗ |
| dsRNA activated protein kinase | 9572845-PKR protein-7 | RNA | Kd | = | 2.8e-06 | 2800 | AptamerBase | — | — | 9572845 ↗ |
| dsRNA activated protein kinase | 9572845-PKR protein-2 | RNA | Kd | = | 4.1e-06 | 4100 | AptamerBase | — | — | 9572845 ↗ |
| dsRNA activated protein kinase | 9572845-PKR protein-3 | RNA | Kd | = | 5.3e-06 | 5300 | AptamerBase | — | — | 9572845 ↗ |
| dsRNA activated protein kinase | 9572845-PKR protein-4 | RNA | Kd | = | 6.2e-06 | 6200 | AptamerBase | — | — | 9572845 ↗ |
| dsRNA activated protein kinase | 9572845-PKR protein-5 | RNA | Kd | = | 6.6e-06 | 6600 | AptamerBase | — | — | 9572845 ↗ |
| Interleukin 17 F/F | 21524680-IL17A/F-2 | RNA | Kd | = | 1.93e-05 | 1.93e+04 | AptamerBase | — | — | 21524680 ↗ |
| Interleukin 17 F/F | 21524680-IL17A/F-1 | RNA | Kd | = | 3.75e-05 | 3.75e+04 | AptamerBase | — | — | 21524680 ↗ |