DNA_gyrase

Synthetic_Pool_1; Synthetic_Pool_2 · 8 runs in PRJNA1406499

UniProt Q5SHZ4 ↗ BioProject PRJNA1406499 ↗ JSON ↗

Organism

Thermus thermophilus

Nucleic acid

DNA

Rounds available

R0,L0

Sequences indexed

10,000

Top enriched sequences

More via API →

Sequence	Length	log₂ FC	P(active)	Class	Monotonicity
GCCCTCATCAAGCTCCCATTAGGACGAACGCGCATAGGATATGAATGGGCGCGAACGTCGGTTAAAGGGTTGGAAGTGATTAACCGCACGGGCGTTACAGAGTTACGTACTGATA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:fabb30299a51	115	-9.80	—	strong_negative	-1.00
CCCTGGCACCAGGCGCGTCTTCACAGGTCGTATGGGTAAAGCAAGGGAATATAGCGGTCGAAGGTGGGATAATAACTTGGAATTGATTGTTACCGGCGTCAATCTTCTGGGAAGA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:fe4194d38533	115	-9.80	—	strong_negative	-1.00
CCATTGGCACCGTGTAAATCTGCTACGGGTAACCAATGGCGACACTGCTTTAGTATGGCTGTGTCTAGGATGAGGTGAGATAAAGGAAGAGACATCGACCTGGGTCGTATTCATC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:59e5a28b42c4	115	-9.80	—	strong_negative	-1.00
ACATGCACTGGAGGGTTAGACCTGGCAGCTGTGACGGATTAATACCGTTCGTCGCGACGACCTTTAAGGTAGAAGGGAACTAGGGTGGCTACTAGTAGCCCTATGCAGGGTGTGG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:9b2838d1887b	115	-9.80	—	strong_negative	-1.00
ACGTGAGCGGGAGTGGCCTCAATGACCAGACGCTGTGTCAAGATGGGCACGATATAGGTTCTCGGGGCTCTTGGCGATACGTGGGGAGACAAGATGGATAAGTAACCACTTGATG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:8fff024146bb	115	-9.80	—	strong_negative	-1.00
ACAGGGGGTCCACTGGTCGCGAAACGATGAGCTGGAAAGTTGGACCGGGCTCACGGGGGTCGGTATGTCTTATGCATAAAGAACTCATGGCGCCCCCTACGTTCTCTGTTGCTGT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:8ceb3e863d9e	115	-9.80	—	strong_negative	-1.00
ATGGACTCGCTGTGGCACAACAAGCACGGGGAATGGTCACGAGCACACCGGCAAGGGGTGTAATTTGACCGCACTTGGACTTCATTTAAGTCTCGTGGGGTCCCCGGTCGATAGC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:e09e1214a1a5	115	-9.80	—	strong_negative	-1.00
GAGGATGTATCTTAGGAGGACCGGCGGGTCCGTGGTTCAGGTGTATGTCTACTATTGCTGTATAGGGGGCGTTCTTATTTGCCTTAGTAATTTATCCGCGTAGTTGGCAGCGGCT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:745e6e975652	115	-9.80	—	strong_negative	-1.00
CGTGTTCCGATGTCATGGTTGCAGCGGTTGGTATGTGGCGAATGCGAAGTTAAGGACAAGTAATTGGATTATGGGACGTGGTTTACTTGAAAAAGCGGCTTAGGGTTGTATATGC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:95beb3d16dff	115	-9.80	—	strong_negative	-1.00
TTGTATTGGGACTCATCGGTGCAAAGGGGGGCGTCTGGCTAAAACCATTCTTTGTAGGTGCACACTCAAGATCAGTCCTCCGACTCGTCCGGTGTACGTCCTCAGCTACCTTTCA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:a63a955f1851	115	-9.80	—	strong_negative	-1.00
CTGAGTGATTTGCTATCCATGGCGTTTAGTGAGCAACTCTCGACGTTGTTAGCATAGGATGTACGTTGGATTATACGACTATAAAGTACGTGGTAGGTCACATGGGGGTAACAAC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:84f342e3516b	115	-9.80	—	strong_negative	-1.00
AGAGGTATTCTCACAGCGAAGTGTGAGTACTGGTTAACATTGCTGGTTGTAGAGGGCGGACCGAGGTGACGGACCTGTACATAGAGAGATGGCCTTGGATCCTTCGAGCGTCATT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:27134bb69703	115	-9.80	—	strong_negative	-1.00
GATAGGTAGAGACGGGGGCCTATCTAGGTTAACTTAATCTCTGTGCGAGTATTAGCCGTGCCGGGCTAGGTCCAAGTATACCCAGTTGTTTTGCGTTGGCAGGTGCGGGGCCAGA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:ce602a65f219	115	-9.80	—	strong_negative	-1.00
AGAAGCGCAAAAACGCTTGTTGGCATTGAAGCAACCGGACGTAAAGCTAACCAGAGCGCGTGGTTTTAGACAAGGAGGTACTGTTAGCCAAGACGGTTCATTTTTCCTGTGATGA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:d6d6f3dc39cc	115	-9.80	—	strong_negative	-1.00
CCAGGAGGTTCTTTGTTGGGGTGTACTGAACCGCCAAGCCGGGGCGGCTGTGCGTGAAGTCGATTGGTGGTTGCAACGTGCTACTAACGGAGCCAGGGGCCGGTTACGTCGGGGT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:7b7ddd17102e	115	-9.80	—	strong_negative	-1.00
CGATTCATAATTGCTGCGTGCTTGACTTCCCTTGTGGGTAGGTCATTCAGTATGGGTATCCCGAGTTGTGCGCGCTAGATCGTGTGGACACCGCTGAATGGAGATAGGCAGTCAG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:dbd3fe219b52	115	-9.80	—	strong_negative	-1.00
GGTTCGGGGTAAGTTCGGCCGGTCACATACGTTGCTCTGTGGCGTTAAGCTCGGGTAGGAGGCAGTCACATGTATCCGGGTACCAGCGCGTTCCGGTAGGACCAGTCTGAGCCGG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:caf13908a460	115	-9.80	—	strong_negative	-1.00
TGTGATTTGCGTACGACAGTTCAGACGGGTTAGGCTGGCGTTGAATTGCTGCCGGTTTTGCTTTAAGGCGGGGCCGGTTAATGTTCTAAAGTTGTCGTTTGGAGGAAACGCAATG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:ae337507f88b	115	-9.80	—	strong_negative	-1.00
TGTGGTTGTAAGAATGGCATATGTAATCCATGGCCCCGCTCAATTGCCTGGACACGTTGCGGGAGGTATAGAAGGCTTCACACGGGGGTCGGTCGGTCGACCACTATAATTGGCG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:7dec38d479e5	115	-9.80	—	strong_negative	-1.00
CGGCATGCGTGATTGCTGAAGATCGTCGAGGGCTGTGATCAATGCTTTAGATTGTAGTTGAATTAGGGTATTAGCTTAAAGTGTGTGTTCGGCTCATCAACAGAGTGTAACTTGA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:4a6dbd515cef	115	-9.80	—	strong_negative	-1.00
ATACTATGGGAATTGCGACACAAATGCGAAGATGATTGGGGCACACCCCGTACCGTTGCGAGGAAAGGGTAAACGTGCGCTTCCTGTGCGGAAGACATGCATGATTGTACGCTAG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:830e74c10c0b	115	-9.80	—	strong_negative	-1.00
TGCGTTTGATGCGGTGATGCCGTTCATCATTCACGTTCTACGTAGAAAACTCGGATGAGGACTCGATAAAAGTGTGAATACTTCGAAGTCTGGGGAAGATTACCGGAGGATTTTC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:a9d41c6ea09f	115	-9.80	—	strong_negative	-1.00
TAGCGTGCTATTCAGTGCCTACTATGGCGTGTGGTGCACTTGTAATGTGAACCGATGCAGGCCGTGTTACCATGATAACTGGTACGTGCTGGGATCGGGAACACAATAGGTTCGC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:15f869b47a51	115	-9.80	—	strong_negative	-1.00
GTTTACAACCGTGACGAAGGAAGAATACTCACATGAGTTCCGGTATGCTTGTATGGTTTTGTAACTGGGGTAAGGACTGCATTGATGAGCCCAGGGCTGGGTAGCTAAGTCCAGC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:acad0b594352	115	-9.80	—	strong_negative	-1.00
GTAGGGAAGGATAATGGGTAAGAACCATGTTTTCGATAAGTGTCAACAGTGTCTTATTCTGTTGCATTGCGTCCCAGGTGATAGGTATCGTGCATTGTCAGATGTGGACAGAGTA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:84467e5b0660	115	-9.80	—	strong_negative	-1.00
CGAGGCATTAAATGGGATTAGCGATCGGTCCCGGCGTTGTAAGGGATGCTGTTTCGGTTTCCTCGTCCAGGCTTTGTACTGTTGGATGACCAAAGGTGTTGGTTTCTAAGGCTGA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:f9d87152cf7d	115	-9.80	—	strong_negative	-1.00
ATATGGAAAGCTAGAGACGATAGCCGATGTGTAGTTGGATACTTTCTAACTGGACTGAGGTAATGGTTGGACAAGCGTTGAACGGTAGCAAGACATTTCTCGATCACCTGACGTT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:b731e9e71ca7	115	-9.80	—	strong_negative	-1.00
CGGTTAACACTCATCTAATCTTCGGTGGGCATTGCGTCGGGGACTTTTTTATGGGTTGGTGAAGTTAATGCGTTGTTGTGAGTACTGACGCACATGTGCATCCATATTTCTTCAC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:b60d5b15017a	115	-9.80	—	strong_negative	-1.00
CAAGTGATGGTCAAACTCGGGCGTAATCGAGTTGGTACGGCCTAGATATGAGGACTTCATTTCCACGAGTTAGTTGATACGATGTTCGCACTTAGTCCTTTTGAGATGATCGGAC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:83ebcc5f39b1	115	-9.80	—	strong_negative	-1.00
CATCGCTTTGCAATACGTGGAATTTGGGTGGTGCCTTCGGTTATCGCGGTTTGGGGCGCACGACGGGTGGAGTAATGGCACGATTCAGGCAGGGCCTATGCCGTAATCAAGAGTG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:ed2185d7fde7	115	-9.80	—	strong_negative	-1.00
AAGTTAGAAGTAAGGGGTTTTTGAACCTATATATGTTTTGATGGAATACAGGTATGAAACTAGTGAGGCGACCTTGCCAACCTGTAAGTGGAGGAAAGCGACGACGTTTCTGGTG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:d9d76898f7ba	115	-9.80	—	strong_negative	-1.00
GGGGGAACATTGGAATGCAATATGTTCTTGGACCGGTGTATGTTCCGAGGGGAATCGGTGTCTATTTTTGCAATCTGGTCGTCAGATAATGTTTATGGGGTCGCATAAGAAGGAG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:93dc827705ab	115	-9.80	—	strong_negative	-1.00
GCGGTACGATATGATGAATCTGGTTACTGTCTGGACAAGTTTCCTTTTGAAAAGTAAACAACACCGGAACAAGGGCAAGATCCGGCACATCTGAGGAGTCGAATGGACGGAGCAG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:4e3cb0cfcf27	115	-9.80	—	strong_negative	-1.00
GTTGGGACGGGGTATTCGAGGGTATATGACGGTGCGCTTTCCTAGTTTGGCGAAGGGTTTATATAATATCCTGAGTGGCGGCCTCTCCCAGCGGGACGCATGGCTGGTCATGGAT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:c9e2cedee635	115	-9.80	—	strong_negative	-1.00
TGGTATCGAACAGTGTGGTGTGAGGAGTAGGCGGGGGGACTGCAAATAACAACGACGCTGGCTGGAGTGGCGGACAGCTATGGCCAGAGTGATGAGGGACGGCCCTCGTAGACTC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:4cefe4af1a88	115	-9.80	—	strong_negative	-1.00
GTCATCCAGGGGTTGGCGGAAATACGACGGAATTCCTGTTCCTGAAGATGACGAGGGAACGGTGCAGGTAACCGGTCTGAGGGCGACGAATACCGTGTCTTGGGTCTAAGAGAGA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:9ba23f684bd8	115	-9.80	—	strong_negative	-1.00
TCGGACAATAGACGACCGTCGTGGACCTTAGCGGTATTCCAGCGGTTCAGCTGGGGCTGGTCAGTGTGGGGAGGTAGTTATCTTGTGGCGGATCAAATTACAGGTAGTGCCCTAG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:118acebb1598	115	-9.80	—	strong_negative	-1.00
CCGGGTCGTGCGGTGCAATTTCGCGTGAAGGCGGGGTAGCGTGTGTGGGCTATGTTGTAGGCATCTAGCGGTTGATGGAGATCTCCGGGTTTGTGCATGTAATAACCTATCTAGG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:2caf0f36c610	115	-9.80	—	strong_negative	-1.00
CGGCGGGTTTGCGATTTGAGATGGTTTCTTAGCTTTGGTGTGGTGAGGTCGTCGTGGGTGTCAAGCAAAGTCACGCTGCTGTAAGTAGCCTTAGGCTTAAACTTCACGGCCAGGG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:d9c01bc200c7	115	-9.80	—	strong_negative	-1.00
ACTGGAGTATTCGATCCGTTTAAGTTGGGCCCCTTACCGATCCGCTATGTGGTGGACTTTTTCGGATGCGGGCCAAATTGAGGAAGTTTGGGGTGTGATTTCGATTACAATAACG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:7bf0b1c030a2	115	-9.80	—	strong_negative	-1.00
ATCCGTGGAGTATAAGGTAGAAGGCGATGCTTCTAGGGTGACGTATATTTATATGCAAGAGTATTTGGTTTCGTAAGAGGATTAATCCGGAGGGGGCCCAGGGGCATTGTGCGAT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:2c74b7d23925	115	-9.80	—	strong_negative	-1.00
ATATCGAGCTGTAGGAGAAGTTCCGTCTGGAATTGATAGTTGCTTGTCACGGCGGCATGGCGTTAGGCTGCAGAGACTGCTTCCTGAGGCCTGACTCACGATTGTAACGGGCGGA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:b0e273b148ad	115	-9.80	—	strong_negative	-1.00
AGGTCAACGACGATTCATCAGAGGCCTATGTCGGGCTAACGTAGATCCGTCAGAAATTGTATAGACTCAGTTTGGAGGTTTGGGTTTGCAGCTTTTGGTAGTCTGGGAAAAATAA PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:337913f42499	115	-9.80	—	strong_negative	-1.00
GGGCTTTACTCTGAAATGGGGCGTGGTAAAAGAGCTGGTGTTAGTTGTATATGCAGCAAATGGTATATATCGTTCAGTAGCTATGATAGCTAAGGGCGTCAGTACTGAACTGAGT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:bfaea41a169d	115	-9.80	—	strong_negative	-1.00
GGTAGCTGTGCGCGGGGGTGACGGGCGTGAGAGGAGAGACTCATGGACCGTAAATGTGGGAAGATCGCACCTACGAAGTGTTGGTATAGTAGTTATTGCCAGTAGGCAGGTCGTT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:e2d61f44c645	115	-9.80	—	strong_negative	-1.00
GAACTCCATGCATCGGCACAAGTGCGTGTTCCATGTCGCACTTAAACTCAGTAGGTATGTGTCGGGATGTGTGTCGGTGAGGTACCGGGTGCGCATATTTTCGCTGTTTCAGCGT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:7e419a3e98ca	115	-9.80	—	strong_negative	-1.00
GGAGGAAGGCTATAGTGGTGCGCGTTTCGCCATCGTACAGTTGAACTTGGAACGTTGATTGTCGCGATCGTAATTGGCGTGTGGGAGAGATTCTACTTTTAAGGGGAACATGGGT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:5e3d3a8a285b	115	-9.80	—	strong_negative	-1.00
TCCTTGGTTGAATTGTTACTCGAGGGCGTGGATCAACGGGCCAATTGTGTTAAGAGGCAGATGAGAAGTGGTGTTTAACTGCCACGAGGTGGTGGTAGGTCCCGTGTATGGACTT PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:e00e565c3d62	115	-9.80	—	strong_negative	-1.00
GTTGGAAGTGGTGGGACCGAGAACGGGGCCATTGGGGTGATGTATAAGTGGGGCTTCTCTGGTCAATCTGAGAGTTATGATAAGGGACGGCGGTGGACGCTTTGATATTTGATAG PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:fdc2ff265b52	115	-9.80	—	strong_negative	-1.00
TCGATGGGTGTCTGTCGGTAGAACGACCGGAGCACGGCGTAGGGCAGATAGAGCGATTTCAAAGGTTTGTTTGGCGGGTTGACTGGGTCGATTTCATGTTTTGTCTCCGTGGCGC PANAPTA:Q5SHZ4:DNA_gyrase:PRJNA1406499:L0:3d144af29f6d	115	-9.80	—	strong_negative	-1.00

SELEX rounds

R0 L0 ·final

Structural & language-model features

JSON ↗

Pre-computed feature catalog (paths only — files served separately).

Residues

634

FASTA

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ESM-2 mean

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ESM-2 per-residue

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