IL-10RA: registration proposal
PRJNA315881 · Data group 2631
Source-qualified proposal prepared
Primary methods and archive experiments report human IL-10RA-Fc. Q13651 is a human IL10RA reference; the historical 677-entry registry has no equivalent entry.
Current retained data
10,000Retained candidate records
2Retained round records
20,000Sequence–round observations
Source-reported material
- Catalogue number
- Not established
- Fusion component
- Fc
- Material type
- source_reported_protein_fusion
- Taxonomy ID
- 9606
- Source-reported material
- human IL-10RA-Fc fusion protein
- Species
- Homo sapiens
- Supplier
- Novus Biologicals
- Target component
- human IL-10RA
Reference and relationship
- Reference accession
- Q13651
- Reference database
- UniProtKB
- Gene
- IL10RA
- Organism
- Homo sapiens
- Reference scope
- gene_and_species_reference_for_source_named_fusion_material
The evidence and limitations below define how the reference relates to the actual experimental material.
Sources and evidence positions
- Human IL-10RA-Fc and RNA library reportedMethods: material preparation and RNA selection
- Archive identifies fusion material and pooled roundsExperiment title; SRR3279660 pools rounds 1–4
- External human gene/species referenceGene IL10RA; human taxonomy 9606
Field corrections
| Field | Original value | Current value | Basis |
|---|---|---|---|
| registry_reference_entity | Not established | IL10RA/Q13651/human | 677-entry registry equivalence review found no existing entity |
| assayed_material | legacy label IL-10RA; construct unspecified | source-reported human IL-10RA-Fc fusion protein | primary methods and both archive experiment titles agree |
| source_group.registry_relation | Not established | source_qualified_selection_material | source project and legacy group identity agree |
| source_library_classification | DNA | RNA | primary method reports recovered RNA and in vitro transcription; imported DNA retained as source history |
| canonical_round_mapping | retained labels L0,R5 | labels retained with pooled archive qualification | SRR3279660 pools source rounds 1–4 and SRR3279661 is source round 5; no barcode-level retained mapping accepted |
Remaining evidence gaps
- Exact Fc-fusion construct boundaries, catalogue, lot and sequence identity are not established.
- Q13651 is a gene/species reference, not an accession explicitly assigned to the fusion construct in the checked paper.
- Archive run/barcode/fraction to retained candidate or observation mapping remains incomplete; control-binding candidates may be present.
- No independent human scientific approval or source-rights approval is supplied by this metadata review.